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Target
Sialidase-1
Ligand
BDBM50649622
Substrate
n/a
Meas. Tech.
ChEMBL_2490838
IC50
20000±n/a nM
Citation
 Zhou, W; Yang, W; Jiang, P; Gou, S A Lysosome-Targeting hNEU1 Inhibitor Treats Myocardial Infarction: A Potential Therapeutic Breakthrough. J Med Chem 67:16899-16911[PubMed] 
Target
Name:
Sialidase-1
Synonyms:
NEUR1_HUMAN | NEU1 | NANH | Sialidase 1
Type:
PROTEIN
Mol. Mass.:
45463.28
Organism:
Human
Description:
ChEMBL_960639
Residue:
415
Sequence:
MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
  
Inhibitor
Name:
BDBM50649622
Synonyms:
CHEMBL5619339
Type:
Small organic molecule
Emp. Form.:
C20H35N3O5
Mol. Mass.:
397.52
SMILES:
CCC(CC)O[C@@H]1C=C(C(=O)OCCN2CCOCC2)C[C@H](N)[C@H]1NC(C)=O
Structure:
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