Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM10849
Substrate
n/a
Meas. Tech.
ChEMBL_548098 (CHEMBL1033447)
Ki
17000±n/a nM
Citation
 Eder, C; Schupp, P; Proksch, P; Wray, V; Steube, K; Müller, CE; Frobenius, W; Herderich, M; van Soest, RW Bioactive pyridoacridine alkaloids from the micronesian sponge Oceanapia sp. J Nat Prod 61:301-5 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptors A1 | AA1R_RAT | Adora1 | Adenosine receptor
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rat
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM10849
Synonyms:
CHEMBL113 | 1,3,7-trimethyl-3,7-dihydropurine-2,6-dione | 1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | Caffeine (1,3,7-trimethylxanthine) | caffeine
Type:
Small organic molecule
Emp. Form.:
C8H10N4O2
Mol. Mass.:
194.08
SMILES:
Cn1cnc2c1C(=O)N(C(=O)N2C)C
Structure:
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