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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50253244
Substrate
n/a
Meas. Tech.
ChEMBL_539777 (CHEMBL1034995)
EC50
310±n/a nM
Citation
 Leopoldo, M; Lacivita, E; De Giorgio, P; Fracasso, C; Guzzetti, S; Caccia, S; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III. J Med Chem 51:5813-22 (2008) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT7 | 5-HT7L | Serotonin 7 (5-HT7) receptor | 5HT7R_CAVPO | HTR7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49632.36
Organism:
Guinea pig
Description:
5-HT7 HTR7 GUINEA PIG::P50407
Residue:
446
Sequence:
MMGVNSSGRPDLYGHLHSILLPGRGLPDWSPDGGADPGVSTWTPRLLSGVPEVAASPSPSWDGTWDNVSGCGEQINYGRAEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSAAKHKFPGFPRVQPESIISLNGMVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTACSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPECVLQNSDYCRKKGHDS
  
Inhibitor
Name:
BDBM50253244
Synonyms:
4-(2-Diphenyl)-N-(4-pyridinylmethyl)-1-piperazinehexanamide | CHEMBL494709
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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