Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM22774
Substrate
n/a
Meas. Tech.
ChEMBL_565117 (CHEMBL955131)
IC50
>50000±n/a nM
Citation
 Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem 17:2276-81 (2009) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
Mitogen-activated protein kinase phosphatase 3 | MAP kinase phosphatase 3 | DUS6_RAT | Dusp6 | Mkp3 | MKP-3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rat
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM22774
Synonyms:
1,4-Benzoquinone | benzoquinone | cid_4650 | CHEMBL8320 | cyclohexa-2,5-diene-1,4-dione | Benzil-related compound, 53
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: