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Target
Retinoic acid receptor gamma
Ligand
BDBM50285920
Substrate
n/a
Meas. Tech.
ChEBML_195985
EC50
34±n/a nM
Citation
 Beard, RL; Colon, DF; Klein, ES; Vorse, KA; Chandraratna, RA Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acids Bioorg Med Chem Lett 5:2729-2734 (1995)    Article 
Target
Name:
Retinoic acid receptor gamma
Synonyms:
NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50345.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458016
Residue:
454
Sequence:
MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
  
Inhibitor
Name:
BDBM50285920
Synonyms:
2-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-thiazole-5-carboxylic acid | CHEMBL93577
Type:
Small organic molecule
Emp. Form.:
C21H25NO2S
Mol. Mass.:
355.494
SMILES:
C\C(=C/c1ncc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Structure:
Search PDB for entries with ligand similarity: