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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50104412
Substrate
n/a
Meas. Tech.
ChEMBL_216814 (CHEMBL816393)
pH
6.8000±n/a
Ki
8400±n/a nM
Comments
extracted
Citation
 Igarashi, Y; Ichikawa, M; Ichikawa, Y Synthesis of a new inhibitor of α-fucosidase Bioorg Med Chem Lett 6:553-558 (1996)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucoside fucohydrolase | Tissue alpha-L-fucosidase | FUCO_HUMAN | FUCA1 | Alpha-L-fucosidase I
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Human
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50104412
Synonyms:
(S)-5-Methyl-piperidine-3,4-diol | CHEMBL86305
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC1CNC[C@H](O)C1O
Structure:
Search PDB for entries with ligand similarity: