Reaction Details
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Probable alpha-glucosidase Os06g0675700
Ligand
BDBM50320827
Substrate
n/a
Meas. Tech.
ChEMBL_639182 (CHEMBL1168035)
pH
5.0000±n/a
IC50
45000±n/a nM
Comments
extracted
Citation
Kato, A; Yamashita, Y; Nakagawa, S; Koike, Y; Adachi, I; Hollinshead, J; Nash, RJ; Ikeda, K; Asano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem 18:3790-4 (2010) [PubMed] Article More Info.:
Target
Name:
Probable alpha-glucosidase Os06g0675700
Synonyms:
AGLU_ORYSJ
Type:
PROTEIN
Mol. Mass.:
96348.92
Organism:
Rice
Description:
ChEMBL_796387
Residue:
885
Sequence:
MMGSPPAPPARRLGALAVFLLALFLAAPWGVDCGYNVASVAGSKNRLRARLELAGGGGGAAPELGPDVRRLSLTASLETDSRLHVRITDADHPRWEVPQDVIPRPSPDSFLAATRPGGGRVLSTATSDLTFAIHTSPFRFTVTRRSTGDVLFDTTPNLVFKDRYLELTSSLPPPGRASLYGLGEQTKRTFRLQRNDTFTLWNSDIAAGNVDLNLYGSHPFYMDVRSGGGGGGGAAHGVLLLNSNGMDVIYGGSYVTYKVIGGVLDFYFFAGPSPLAVVDQYTQLIGRPAPMPYWSFGFHQCRYGYKNVADLEGVVAGYAKARIPLEVMWTDIDYMDAYKDFTLDPVNFPADRMRPFVDRLHRNGQKFVVIIDPGINVNTTYGTFVRGMKQDIFLKWNGSNYLGVVWPGNVYFPDFLNPRAAEFWAREIAAFRRTLPVDGLWVDMNEISNFVDPPPLNAIDDPPYRINNSGVRRPINNKTVPASAVHYGGVAEYDAHNLFGFLEARATHDALLRDTGRRPFVLSRSTFVGSGRYTAHWTGDNAATWEDLHYSINTMLSFGLFGIPMIGADICGFGGNTTEELCSRWIQLGAFYPFSRDHSAIGTVRRELYLWESVARSARKALGLRYRLLPYLYTLMYEAHTTGAPIARPLFFSYPGDVETYGIDRQFLLGRGVLVSPVLEPGATTVTAYFPAGRWFSLYDFSLAVATKTGKRVTLPAPADTVNVHVAGGNILTLQQPALTSSRVRQSVVHLLVALADDGTATGDLFLDDGESPEMAGPRSRWSQIKFSGATESGGGVVRVRSHVVHDSYAPSRTMAIGKVVLMGLRSAAPPKGFAVYANGVQVNASTAVGGAAGSPEKGALGVAHVSGLTLVVGQEFDLKVVMTY
Inhibitor
Name:
BDBM50320827
Synonyms:
beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMBL1163562
Type:
Small organic molecule
Emp. Form.:
C11 H21 N O3
Mol. Mass.:
215.28934
SMILES:
C[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)N[C@H]1CCC=C |r|
Structure:
