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Target
Ribonuclease pancreatic
Ligand
BDBM50342010
Substrate
n/a
Meas. Tech.
ChEMBL_743585 (CHEMBL1768085)
pH
5.9±n/a
Ki
27±n/a nM
Comments
extracted
Citation
 Samanta, A; Dasgupta, S; Pathak, T 5'-Modified pyrimidine nucleosides as inhibitors of ribonuclease A. Bioorg Med Chem 19:2478-84 (2011) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50342010
Synonyms:
5'-phospho-2'-deoxyuridine-3'-pyrophosphate(P'->5')adenosine3'-phosphate | CHEMBL1765479
Type:
Small organic molecule
Emp. Form.:
C19H26N7O17P3
Mol. Mass.:
717.3677
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2OP(O)(=O)OP(O)(O)=O)n2ccc(=O)[nH]c2=O)[C@H]1O |r|
Structure:
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