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Target
Beta-lactamase SHV-5
Ligand
BDBM50347188
Substrate
n/a
Meas. Tech.
ChEMBL_754353 (CHEMBL1799219)
IC50
>50000±n/a nM
Citation
 Tan, Q; Ogawa, AM; Raghoobar, SL; Wisniewski, D; Colwell, L; Park, YW; Young, K; Hermes, JD; Dininno, FP; Hammond, ML Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii. Bioorg Med Chem Lett 21:4363-5 (2011) [PubMed]  Article 
Target
Name:
Beta-lactamase SHV-5
Synonyms:
BLA5_KLEPN | bla | shv5
Type:
PROTEIN
Mol. Mass.:
31257.78
Organism:
Pseudomonas aeruginosa (g-Proteobacteria)
Description:
ChEMBL_754353
Residue:
286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
  
Inhibitor
Name:
BDBM50347188
Synonyms:
CHEMBL1795571
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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