Reaction Details Report a problem with these data
Target
Adenosine 5'-monophosphoramidase HINT1
Ligand
BDBM50360480
Substrate
n/a
Meas. Tech.
ChEMBL_795618 (CHEMBL1936048)
Ki
103000±n/a nM
Citation
 Bardaweel, SK; Ghosh, B; Wagner, CR Synthesis and evaluation of potential inhibitors of human and Escherichia coli histidine triad nucleotide binding proteins. Bioorg Med Chem Lett 22:558-60 (2011) [PubMed]  Article 
Target
Name:
Adenosine 5'-monophosphoramidase HINT1
Synonyms:
Adenosine 5'-monophosphoramidase | PKCI-1 | Protein kinase C-interacting protein 1 | Protein kinase C inhibitor 1 | HINT1_HUMAN | HINT1 | HINT | PKCI1 | PRKCNH1 | Histidine triad nucleotide-binding protein 1
Type:
PROTEIN
Mol. Mass.:
13803.77
Organism:
Human
Description:
ChEMBL_795618
Residue:
126
Sequence:
MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
  
Inhibitor
Name:
BDBM50360480
Synonyms:
CHEMBL1934756
Type:
Small organic molecule
Emp. Form.:
C21H23N7O5
Mol. Mass.:
n/a
SMILES:
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC(=O)NCCc2c[nH]c3ccccc23)[C@@H](O)[C@H]1O
Structure:
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