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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50029816
Substrate
n/a
Meas. Tech.
ChEMBL_122946 (CHEMBL733231)
IC50
>10000±n/a nM
Citation
 Rendenbach-Muller, B; Schlecker, R; Traut, M; Weifenbach, H Synthesis of coumarins as subtype-selective inhibitors of monoamine oxidase Bioorg Med Chem Lett 4:1195-1198 (1994)    Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
Monoamine oxidase A (MAO-A) | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase type A (MAOA) | Amine oxidase [flavin-containing] A | Amine oxidase (flavin-containing) A | Monoamine oxidase A (rMAO-A) | AOFA_RAT | Maoa | Monoamine oxidase
Type:
Enzyme
Mol. Mass.:
59515.21
Organism:
Rat
Description:
n/a
Residue:
526
Sequence:
MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
  
Inhibitor
Name:
BDBM50029816
Synonyms:
Ro-19-6327 | 5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide | Lazabemide | CHEMBL279390
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: