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Target
Carbonic anhydrase 4
Ligand
BDBM10881
Substrate
n/a
Meas. Tech.
ChEBML_45273
Ki
36±n/a nM
Citation
 Abbate, F; Casini, A; Owa, T; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Bioorg Med Chem Lett 14:217-23 (2003) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | Carbonic anhydrase 4 | Carbonate dehydratase IV | CAH4_BOVIN | CA4 | Carbonic anhydrase | Carbonic Anhydrase IV
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bovine
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM10881
Synonyms:
CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide | MZA3 | Sulfonamide, 2 | Methazolamide, MZA | Methazolamide | sulfonamide 2 | Methazolamide (MZA)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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