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Target
Thromboxane-A synthase
Ligand
BDBM84684
Substrate
n/a
Meas. Tech.
ChEBML_210444
IC50
>1000±n/a nM
Citation
 Tanouchi, T; Kawamura, M; Ohyama, I; Kajiwara, I; Iguchi, Y; Okada, T; Miyamoto, T; Taniguchi, K; Hayashi, M; Iizuka, K; Nakazawa, M Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives. J Med Chem 24:1149-55 (1982) [PubMed]  Article 
Target
Name:
Thromboxane-A synthase
Synonyms:
Thromboxane Alpha | Thromboxane synthase | Thromboxane-A synthase | TXA synthase | Thromboxane A2 Synthase | P450 TxA2 | Thromboxane prostanoid | Cytochrome P450 5A1 | TXS | THAS_HUMAN | TBXAS1 | CYP5 | CYP5A1 | TXAS | Thromboxane A2 Synthase (P450 TxA2)
Type:
Enzyme
Mol. Mass.:
60524.67
Organism:
Human
Description:
P24557
Residue:
533
Sequence:
MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
  
Inhibitor
Name:
BDBM84684
Synonyms:
CHEMBL543494 | 1-Subsituted 1H-imidazole, 21
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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