Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 3B
Ligand
BDBM50013043
Substrate
n/a
Meas. Tech.
ChEBML_3121
Ki
10±n/a nM
Citation
 Rizzi, JP; Nagel, AA; Rosen, T; McLean, S; Seeger, T An initial three-component pharmacophore for specific serotonin-3 receptor ligands. J Med Chem 33:2721-5 (1990) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 3B
Synonyms:
Serotonin 3b (5-HT3b) receptor | 5HT3B_MOUSE | Htr3b | Serotonin 3 receptor (5HT3)
Type:
PROTEIN
Mol. Mass.:
50317.35
Organism:
Mouse
Description:
ChEMBL_3121
Residue:
437
Sequence:
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
  
Inhibitor
Name:
BDBM50013043
Synonyms:
CHEMBL290938 | 3-[2-(5-Methyl-1H-imidazol-4-ylmethyl)-thiazol-4-yl]-1H-indole
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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