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Target
Glutamate dehydrogenase 1, mitochondrial
Ligand
BDBM50368954
Substrate
n/a
Meas. Tech.
ChEMBL_71834 (CHEMBL683665)
Ki
15000±n/a nM
Citation
 Goldstein, BM; Li, H; Jones, JP; Bell, JE; Zeidler, J; Pankiewicz, KW; Watanabe, KA CNAD: a potent and specific inhibitor of alcohol dehydrogenase. J Med Chem 37:392-9 (1994) [PubMed]  Article 
Target
Name:
Glutamate dehydrogenase 1, mitochondrial
Synonyms:
DHE3_BOVIN | GLUD1 | GLUD | Glutamate dehydrogenase
Type:
PROTEIN
Mol. Mass.:
61518.81
Organism:
Bovine
Description:
ChEMBL_71835
Residue:
558
Sequence:
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLVPPARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRSILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLNNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFRVYNEAGVTFT
  
Inhibitor
Name:
BDBM50368954
Synonyms:
CHEMBL610377
Type:
Small organic molecule
Emp. Form.:
C21H27N7O14P2
Mol. Mass.:
n/a
SMILES:
NC(=O)c1cncc(c1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r|
Structure:
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