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Target
Delta-type opioid receptor
Ligand
BDBM50065353
Substrate
n/a
Meas. Tech.
ChEMBL_145498 (CHEMBL752140)
Ki
2.1±n/a nM
Citation
 Shreder, K; Zhang, L; Dang, T; Yaksh, TL; Umeno, H; DeHaven, R; Daubert, J; Goodman, M Synthesis and biological activity of a novel methylamine-bridged enkephalin analogue (MABE): a new route to cyclic peptides and peptidomimetics. J Med Chem 41:2631-5 (1998) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRK1 | opioid receptor, delta 1 | OPRD_HUMAN | OPRD1 | OPRD
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Human
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50065353
Synonyms:
(S)-2-Amino-N-((6S,12R)-6-benzyl-1-methyl-5,8,11-trioxo-1,4,7,10tetraaza-cyclotridec-12-yl)-3-(4-hydroxy-phenyl)-propionamide | CHEMBL88560
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: