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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM81982
Substrate
n/a
Meas. Tech.
ChEMBL_201423 (CHEMBL810656)
Kd
11.6±n/a nM
Citation
 Ronsisvalle, G; Prezzavento, O; Marrazzo, A; Vittorio, F; Massimino, M; Murari, G; Spampinato, S Synthesis of (+)-cis-N-(4-isothiocyanatobenzyl)-N-normetazocine, an isothiocyanate derivative of N-benzylnormetazocine as acylant agent for the sigma(1) receptor. J Med Chem 45:2662-5 (2002) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | SIG-1R | SR-BP | SR31747-binding protein | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 | SGMR1_HUMAN | SIGMAR1 | OPRS1 | SRBP
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Human
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM81982
Synonyms:
CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DITOLYLGUANIDINE | DTG | Tol2Gdn
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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