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Target
Primary amine oxidase
Ligand
BDBM50161142
Substrate
n/a
Meas. Tech.
ChEMBL_306371 (CHEMBL828342)
IC50
>100000±n/a nM
Citation
 Bertini, V; Buffoni, F; Ignesti, G; Picci, N; Trombino, S; Iemma, F; Alfei, S; Pocci, M; Lucchesini, F; De Munno, A Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases. J Med Chem 48:664-70 (2005) [PubMed]  Article 
Target
Name:
Primary amine oxidase
Synonyms:
AMO_PEA | Amine oxidase
Type:
PROTEIN
Mol. Mass.:
76360.57
Organism:
Garden pea
Description:
ChEMBL_306391
Residue:
674
Sequence:
MASTTTMRLALFSVLTLLSFHAVVSVTPLHVQHPLDPLTKEEFLAVQTIVQNKYPISNNRLAFHYIGLDDPEKDHVLRYETHPTLVSIPRKIFVVAIINSQTHEILINLRIRSIVSDNIHNGYGFPILSVDEQSLAIKLPLKYPPFIDSVKKRGLNLSEIVCSSFTMGWFGEEKNVRTVRLDCFMKESTVNIYVRPITGITIVADLDLMKIVEYHDRDIEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGHSVSWANWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAICVFEQYGNIMWRHTENGIPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSIALSGILEIKGTNIKHKDEIKEDLHGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSFEKTSLKTVRIKDGSSKRKSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIPAIPAHPLLTEDDYPQIRGAFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTLAVWTKQNREIVNKDIVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTLSPRDVAWPGCSN
  
Inhibitor
Name:
BDBM50161142
Synonyms:
N-[2-(aminomethyl)phenyl]-N-ethylamine dihydrochloride | CHEMBL557976
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCNc1ccccc1CN
Structure:
Search PDB for entries with ligand similarity: