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Target
Primary amine oxidase
Ligand
BDBM50161146
Substrate
n/a
Meas. Tech.
ChEMBL_306391 (CHEMBL828732)
IC50
17000±n/a nM
Citation
 Bertini, V; Buffoni, F; Ignesti, G; Picci, N; Trombino, S; Iemma, F; Alfei, S; Pocci, M; Lucchesini, F; De Munno, A Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases. J Med Chem 48:664-70 (2005) [PubMed]  Article 
Target
Name:
Primary amine oxidase
Synonyms:
AMO_PEA | Amine oxidase
Type:
PROTEIN
Mol. Mass.:
76360.57
Organism:
Pisum sativum
Description:
ChEMBL_306391
Residue:
674
Sequence:
MASTTTMRLALFSVLTLLSFHAVVSVTPLHVQHPLDPLTKEEFLAVQTIVQNKYPISNNRLAFHYIGLDDPEKDHVLRYETHPTLVSIPRKIFVVAIINSQTHEILINLRIRSIVSDNIHNGYGFPILSVDEQSLAIKLPLKYPPFIDSVKKRGLNLSEIVCSSFTMGWFGEEKNVRTVRLDCFMKESTVNIYVRPITGITIVADLDLMKIVEYHDRDIEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGHSVSWANWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAICVFEQYGNIMWRHTENGIPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSIALSGILEIKGTNIKHKDEIKEDLHGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSFEKTSLKTVRIKDGSSKRKSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIPAIPAHPLLTEDDYPQIRGAFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTLAVWTKQNREIVNKDIVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTLSPRDVAWPGCSN
  
Inhibitor
Name:
BDBM50161146
Synonyms:
4-(aminomethyl)-5-(dimethyl-lambda~5~-azanyl)-N-methylpyridin-3-amine dihydrochloride dihydrate | CHEMBL534467
Type:
Small organic molecule
Emp. Form.:
C9H16N4
Mol. Mass.:
180.2501
SMILES:
CNc1cncc(N(C)C)c1CN
Structure:
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