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Target
Cyclin-dependent kinase 1
Ligand
BDBM7695
Substrate
n/a
Meas. Tech.
ChEMBL_468974 (CHEMBL952119)
IC50
41±n/a nM
Citation
 Kolb, P; Huang, D; Dey, F; Caflisch, A Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model. J Med Chem 51:1179-88 (2008) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | p34 protein kinase | CDK1_HUMAN | CDK1 | CDC2 | CDC28A | CDKN1 | P34CDC2
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Human
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM7695
Synonyms:
4-{2-[(3Z)-2-oxo-4-(propan-2-yloxy)-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide | Oxindole-Based Inhibitor 31
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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