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Target
Thymidine kinase
Ligand
BDBM31915
Substrate
n/a
Meas. Tech.
ChEMBL_474153 (CHEMBL938411)
IC50
900000±n/a nM
Citation
 Focher, F; Lossani, A; Verri, A; Spadari, S; Maioli, A; Gambino, JJ; Wright, GE; Eberle, R; Black, DH; Medveczky, P; Medveczky, M; Shugar, D Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides. Antimicrob Agents Chemother 51:2028-34 (2007) [PubMed]  Article 
Target
Name:
Thymidine kinase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
40204.56
Organism:
CeHV-1
Description:
ChEMBL_474153
Residue:
370
Sequence:
MASHAGHQDSPALDRVAGSAGHGDHPSALLRIYVDGPHGLGKTTTAAALAAALGRRDEIEYVPEPMAYWQTLGGPQTITRIFDAQHRLDRGEISASEAAMAMASAQVTMSTPYAVTESAVAPHIGAELPPGHGPHPNIDLTLVFDRHPVASLLCYPAARYLMGSLSLPTVLSFAALLPQTTPGTNLVLGALPEAVHAERLAQRQRPGERLDLAMLSAIRRVYDMLGNAIVYLQRGGSWRADWRRLSPARSAAASGRPARILPRPEIEDTIFALFCAPELLDETGEPYRVFAWTLDLLAERLRPMHLLVLDYNQAPHHCWMDLMEMIPEMTPTLPATPGSMLTLQLLAREFAREMTSTRGGDVGGEGRETR
  
Inhibitor
Name:
BDBM31915
Synonyms:
HPMPC | Vistide | CDV | Cidofovir | US10071110, Compound Cidofovir
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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