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Target
Segment polarity protein dishevelled homolog DVL-2
Ligand
BDBM50378802
Substrate
n/a
Meas. Tech.
ChEMBL_651099 (CHEMBL1227540)
Ki
1200±n/a nM
Citation
 Zhang, Y; Appleton, BA; Wiesmann, C; Lau, T; Costa, M; Hannoush, RN; Sidhu, SS Inhibition of Wnt signaling by Dishevelled PDZ peptides. Nat Chem Biol 5:217-9 (2009) [PubMed]  Article 
Target
Name:
Segment polarity protein dishevelled homolog DVL-2
Synonyms:
Dishevelled-2 | DSH homolog 2 | DVL2_HUMAN | DVL2
Type:
PROTEIN
Mol. Mass.:
78940.00
Organism:
Human
Description:
ChEMBL_651099
Residue:
736
Sequence:
MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM
  
Inhibitor
Name:
BDBM50378802
Synonyms:
CHEMBL1222068
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: