Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50386790
Substrate
n/a
Meas. Tech.
ChEMBL_859283 (CHEMBL2166571)
EC50
21.88±n/a nM
Citation
 Christiansen, E; Due-Hansen, ME; Urban, C; Grundmann, M; Schröder, R; Hudson, BD; Milligan, G; Cawthorne, MA; Kostenis, E; Kassack, MU; Ulven, T Free fatty acid receptor 1 (FFA1/GPR40) agonists: mesylpropoxy appendage lowers lipophilicity and improves ADME properties. J Med Chem 55:6624-8 (2012) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
G-protein Coupled Receptor 40 | FFAR1_HUMAN | FFAR1 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Human
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50386790
Synonyms:
CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US11905230, Example TAK-875
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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