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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50411243
Substrate
n/a
Meas. Tech.
ChEMBL_425645 (CHEMBL912582)
IC50
99900±n/a nM
Citation
 Chimenti, F; Fioravanti, R; Bolasco, A; Manna, F; Chimenti, P; Secci, D; Befani, O; Turini, P; Ortuso, F; Alcaro, S Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors. J Med Chem 50:425-8 (2007) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Amine oxidase [flavin-containing] B | MAO-B | Monoamine oxidase B | Monoamine oxidase type B | AOFB_BOVIN | MAOB | Monoamine oxidase | Monoamine Oxidase Type B (MAO-B)
Type:
PROTEIN
Mol. Mass.:
58428.94
Organism:
Bovine
Description:
ChEMBL_1501478
Residue:
520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWRTMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEVSALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQTGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVYYKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEERLKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTTFLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
  
Inhibitor
Name:
BDBM50411243
Synonyms:
CHEMBL221629
Type:
Small organic molecule
Emp. Form.:
C15 H10 F2 N2
Mol. Mass.:
n/a
SMILES:
Fc1ccc(cc1)-c1cc([nH]n1)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: