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Target
Alpha-1B adrenergic receptor
Ligand
BDBM50414756
Substrate
n/a
Meas. Tech.
ChEMBL_588344 (CHEMBL1037686)
Kd
280.54±n/a nM
Citation
 Kulig, K; Sapa, J; Nowaczyk, A; Filipek, B; Malawska, B Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity. Eur J Med Chem 44:3994-4003 (2009) [PubMed]  Article 
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
Alpha-1B adrenergic receptor | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | ADA1B_HUMAN | ADRA1B | Adrenergic receptor | Adrenergic alpha1B | Adrenergic receptor alpha
Type:
Enzyme
Mol. Mass.:
56862.13
Organism:
Human
Description:
P35368
Residue:
520
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
  
Inhibitor
Name:
BDBM50414756
Synonyms:
CHEMBL569201
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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