Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 1
Ligand
BDBM50416487
Substrate
n/a
Meas. Tech.
ChEMBL_839183 (CHEMBL2077854)
Ki
7300±n/a nM
Citation
 Dresser, MJ; Gray, AT; Giacomini, KM Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1). J Pharmacol Exp Ther 292:1146-52 (2000) [PubMed] 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
Lx1 | Oct1 | Organic cation transporter 1 | S22A1_MOUSE | Slc22a1 | mOCT1
Type:
PROTEIN
Mol. Mass.:
61521.43
Organism:
Mus musculus
Description:
ChEMBL_1279071
Residue:
556
Sequence:
MPTVDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSPHT
  
Inhibitor
Name:
BDBM50416487
Synonyms:
CHEMBL1236196 | TETRABUTYLAMMONIUM
Type:
Small organic molecule
Emp. Form.:
C16H36N
Mol. Mass.:
242.4632
SMILES:
CCCC[N+](CCCC)(CCCC)CCCC
Structure:
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