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Target
3-oxoacyl-ACP synthase
Ligand
BDBM50062146
Substrate
n/a
Meas. Tech.
ChEMBL_1462635 (CHEMBL3399322)
IC50
7900±n/a nM
Citation
 Allegretta, G; Weidel, E; Empting, M; Hartmann, RW Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD. Eur J Med Chem 90:351-9 (2015) [PubMed]  Article 
Target
Name:
3-oxoacyl-ACP synthase
Synonyms:
PQB biosynthetic 3-oxoacyl-[acyl-carrier-protein] synthase III | YQ19_24710 | pqsD | 2-heptyl-4(1H)-quinolone synthase PqsD | 3-oxoacyl-(Acyl carrier protein) synthase III | 3-oxoacyl-ACP synthase | ERS445055_04170 | PA8380_44470 | PAE221_04722
Type:
PROTEIN
Mol. Mass.:
36357.84
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_109728
Residue:
337
Sequence:
MGNPILAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRYHVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLGLRHIPVLDIRAQCSGLLYGLQMARGQILAGLARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGAGAVVVSAGESLDDGLLDLRLGADGNYFDLLMTAAPGSASPTFLDENVLREGGGEFLMRGRPMFEHASQTLVRIAGEMLAAHELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVDRLGNMASASTPVTLAMFWPDIQPGQRVLVLTYGSGATWGAALYRKPEEVNRPC
  
Inhibitor
Name:
BDBM50062146
Synonyms:
CHEMBL3397065
Type:
Small organic molecule
Emp. Form.:
C11H14O4
Mol. Mass.:
210.09
SMILES:
COC(=O)CCCc1ccc(O)c(O)c1
Structure:
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