Reaction Details Report a problem with these data
Target
C-X-C chemokine receptor type 4
Ligand
BDBM50100599
Substrate
n/a
Meas. Tech.
ChEMBL_1457660 (CHEMBL3368946)
EC50
57544±n/a nM
Citation
 Zachariassen, ZG; Thiele, S; Berg, EA; Rasmussen, P; Fossen, T; Rosenkilde, MM; Våbenø, J; Haug, BE Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4). Bioorg Med Chem 22:4759-69 (2014) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 4
Synonyms:
C-X-C chemokine receptor type 4 | NPYRL | CXCR-4 | HM89 | CXC-R4 | SDF-1 receptor | CD_antigen=CD184 | Stromal cell-derived factor 1 receptor | LCR1 | LESTR | Fusin | Leukocyte-derived seven transmembrane domain receptor | FB22 | C-X-C chemokine receptor type 4 (CXCR4) | CXCR4_HUMAN | CXCR4
Type:
Enzyme
Mol. Mass.:
39754.61
Organism:
Human
Description:
P61073
Residue:
352
Sequence:
MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
  
Inhibitor
Name:
BDBM50100599
Synonyms:
CHEMBL3327366
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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