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Target
Cannabinoid receptor 1
Ligand
BDBM50233619
Substrate
n/a
Meas. Tech.
ChEMBL_1651006 (CHEMBL4000261)
Ki
0.300000±n/a nM
Citation
 Nikas, SP; Sharma, R; Paronis, CA; Kulkarni, S; Thakur, GA; Hurst, D; Wood, JT; Gifford, RS; Rajarshi, G; Liu, Y; Raghav, JG; Guo, JJ; Järbe, TU; Reggio, PH; Bergman, J; Makriyannis, A Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols. J Med Chem 58:665-81 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50233619
Synonyms:
CHEMBL4085404 | US10882838, Example 1.18
Type:
Small organic molecule
Emp. Form.:
C25H33BrO4
Mol. Mass.:
477.431
SMILES:
[H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C1(CCC1)C(=O)OCCCCBr |r,c:4|
Structure:
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