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Target
Carboxylic ester hydrolase
Ligand
BDBM50159655
Substrate
n/a
Meas. Tech.
ChEMBL_1655009 (CHEMBL4004375)
IC50
7.0±n/a nM
Citation
 Singh, H; Singh, JV; Gupta, MK; Singh, P; Sharma, S; Nepali, K; Bedi, PMS Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies. Bioorg Med Chem Lett 27:850-854 (2017) [PubMed]  Article 
Target
Name:
Carboxylic ester hydrolase
Synonyms:
3.1.1.- | CEL | Carboxylic ester hydrolase
Type:
PROTEIN
Mol. Mass.:
63554.81
Organism:
Pig
Description:
ChEMBL_117582
Residue:
585
Sequence:
MGSSELVIWCLACCLAAARAAKLGSVYTEGGFVEGVNKKLSLLGDSVDIFKGIPFAAAPKALENPQRHPGWQGTLKAKDFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKEVSRDLPVMIWIYGGAFLMGSGQGANFLSNYLYDGEELATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGGASVSLQTLSPYNKGLIKRAISQSGVALSPWAIQKNPLSWAKTIAEKVGCPMDDTARMARCLKITDPRALTLAYKLPLTKQEFPVVHYLGFIPVVDGDFIPDDPVNLYANAADIDYLAGTNDMDGHLFATVDLPAVDKDKKTITEEDFYKLVSGFTIVKGPRGANITFDVYTASWAQDSSQETKKKTVVDLETDILFLMPTETAVAQHRANAKSAQTYTYVFAHPSRMPVYPSWYVFGKPFAMIAYWTNFARSGDPNMGGSSVPTHWEPYTLESSKYLEITNKMDSSSMKQDLRTSYLQYWATTYQALPTVADEGAIPVPPTGDSEATPAPPTGDPEATPAPPTGDSEATPAPPPSDAEVAQMPIVIGF
  
Inhibitor
Name:
BDBM50159655
Synonyms:
2-(3-Chloro-phenyl)-benzo[h]chromen-4-one | CHEMBL368236
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: