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Target
Alpha-fucosidase-like protein
Ligand
BDBM50065258
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
6.5000±0.0000
Temperature
310.1500±0.0000 K
Kd
27.0±4.4 nM
Citation
 Lammerts van Bueren, A; Popat, SD; Lin, CH; Davies, GJ Structural and thermodynamic analyses of α-L-fucosidase inhibitors. Chembiochem 11:1971-4 (2010) [PubMed]  Article 
Target
Name:
Alpha-fucosidase-like protein
Synonyms:
Alpha-fucosidase
Type:
Protein
Mol. Mass.:
49785.16
Organism:
Bacteroides thetaiotaomicron
Description:
Q8ABG8
Residue:
461
Sequence:
MKHIAFLSVKWMSVGLGMLSLLLSVASCGDKEYGDAMNEAQLMNDIEVNVGSSLPLAVGMDFVLDYKPVPENVTNPEITLTSSDENVVSVSQDGRVTAKMIGKAYINLSQSTAFETLKTIEVQVMPVATAIELENVELFEGTNKKVIVNVTPSDGYNVFDWKSDNEEVATVADDGTITGKKPGTANISVSSQDGSQLTATAVVTVKEVIPIDKITLSEPGYDMMIGDKTLINCLLEPIDASVGLLSWSTTNDRVATVDADGLVTAVGAGEAEIIAQDPLSGLSASIAVKVVGEGVVSLSLSYVRNQDELKALGWGFGQTPASVNFDAEGMTVNMSLQSNSKYRADLKMASNDRPVVLNIGTYRYLAFRMDVPGNGSLKLDTNKGDYGNNPTGVLAEDSQVIYYDLQAKPYFPTDAPSDKLTTFQLKIADVTVQPYSYKVYWVRTFKTLEDLKVYVEKENNK
  
Inhibitor
Name:
BDBM50065258
Synonyms:
CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol | Fucosidase Inhibitor, 3 | (2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: