Reaction Details
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Gamma-aminobutyric acid receptor subunit alpha-6
Ligand
BDBM81951
Substrate
n/a
Ki
134±n/a nM
Comments
PDSP_689
Citation
Hadingham, KL; Garrett, EM; Wafford, KA; Bain, C; Heavens, RP; Sirinathsinghji, DJ; Whiting, PJ Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors. Mol Pharmacol 49:253-9 (1996) [PubMed] More Info.:
Target
Name:
Gamma-aminobutyric acid receptor subunit alpha-6
Synonyms:
GABA A alpha6 | GABA receptor alpha-6 subunit | GBRA6_HUMAN | GABRA6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51029.60
Organism:
Human
Description:
GABA A alpha6 0 HUMAN::Q16445
Residue:
453
Sequence:
MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
Inhibitor
Name:
BDBM81951
Synonyms:
NSC_104999 | CAS_104999 | DMCM
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCc1c2c3cc(c(cc3[nH]c2cnc1C(=O)OC)OC)OC
Structure:
