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Target
Bone morphogenetic protein receptor type-1B
Ligand
BDBM148379
Substrate
n/a
Meas. Tech.
Enzyme Assay
IC50
4183±n/a nM
Citation
 Alimardanov, A; Cuny, GD; Grewal, GS; Lee, A; McKew, JC; Mohedas, AH; Shen, M; Xu, X; Yu, PB BMP inhibitors and methods of use thereof US Patent  US10017516 Publication Date 7/10/2018 
Target
Name:
Bone morphogenetic protein receptor type-1B
Synonyms:
BMR1B_HUMAN | BMPR1B | ALK-6 | ALK6 | Bone morphogenetic protein receptor type-1B (BMPR1B)
Type:
Enzyme
Mol. Mass.:
56939.41
Organism:
Human
Description:
O00238
Residue:
502
Sequence:
MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
  
Inhibitor
Name:
BDBM148379
Synonyms:
US9682983, 35 | US10017516, Compound 35
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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