Reaction Details Report a problem with these data
Target
Promotilin
Ligand
BDBM85998
Substrate
n/a
Ki
144.54±n/a nM
Comments
PDSP_6207
Citation
 Thielemans, L; Depoortere, I; Vanden Broeck, J; Peeters, TL The motilin pharmacophore in CHO cells expressing the human motilin receptor. Biochem Biophys Res Commun 293:1223-7 (2002) [PubMed]  Article 
Target
Name:
Promotilin
Synonyms:
Promotilin | MOTI_HUMAN | MLN | Motilin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12919.83
Organism:
Human
Description:
Motilin 0 HUMAN::P12872
Residue:
115
Sequence:
MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
  
Inhibitor
Name:
BDBM85998
Synonyms:
Erythromycin-B
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC[C@@H]1[C@@H]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)C
Structure:
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