Reaction Details Report a problem with these data
Target
Promotilin
Ligand
BDBM86313
Substrate
n/a
Ki
3090.30±n/a nM
Comments
PDSP_6110
Citation
 Thielemans, L; Depoortere, I; Perret, J; Robberecht, P; Liu, Y; Thijs, T; Carreras, C; Burgeon, E; Peeters, TL Desensitization of the human motilin receptor by motilides. J Pharmacol Exp Ther 313:1397-405 (2005) [PubMed]  Article 
Target
Name:
Promotilin
Synonyms:
Promotilin | MOTI_HUMAN | MLN | Motilin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12919.83
Organism:
Human
Description:
Motilin 0 HUMAN::P12872
Residue:
115
Sequence:
MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
  
Inhibitor
Name:
BDBM86313
Synonyms:
CAS_114-07-8 | NSC_12560 | erythromycin-A
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
Structure:
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