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Target
Stromelysin-2
Ligand
BDBM92445
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
6.8000±0.0000
Temperature
298.1500±0.0000 K
Ki
3106±0.0 nM
Citation
 Devel, L; Beau, F; Amoura, M; Vera, L; Cassar-Lajeunesse, E; Garcia, S; Czarny, B; Stura, EA; Dive, V Simple Pseudo-dipeptides with a P2' Glutamate: A NOVEL INHIBITOR FAMILY OF MATRIX METALLOPROTEASES AND OTHER METZINCINS. J Biol Chem 287:26647-56 (2012) [PubMed]  Article 
Target
Name:
Stromelysin-2
Synonyms:
Matrix metalloproteinase 10 | MMP10_HUMAN | MMP10 | STMY2 | Matrix Metalloproteinase-10 (MMP-10)
Type:
Enzyme
Mol. Mass.:
54143.02
Organism:
Human
Description:
P09238
Residue:
476
Sequence:
MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
  
Inhibitor
Name:
BDBM92445
Synonyms:
US8691753, 105 | Inhibitor, 10
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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