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Target
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
Ligand
BDBM50070942
Substrate
n/a
Meas. Tech.
SPA Assay
pH
7.3000±0.0000
Temperature
295.1500±0.0000 K
IC50
1800±200 nM
Citation
 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys 425:51-7 (2004) [PubMed]  Article 
Target
Name:
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
Synonyms:
Fucosyltransferase IV | Fucosyltransferase 6 | Fuct IV | Alpha-(1,3)-fucosyltransferase IV | FUT6_HUMAN | FUT6 | FCT3A
Type:
n/a
Mol. Mass.:
41871.43
Organism:
Human
Description:
P51993
Residue:
359
Sequence:
MDPLGPAKPQWSWRCCLTTLLFQLLMAVCFFSYLRVSQDDPTVYPNGSRFPDSTGTPAHSIPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQEESRYQTRGIAAWFT
  
Inhibitor
Name:
BDBM50070942
Synonyms:
(-)-Epigallocatechin-3-o-gallate | (-)-Epigallocatechin gallate | Epigallocatechin monogallate, B | cid_65064 | CHEMBL297453 | EGCG | Epigallocatechin 3-gallate | (-)-epigallocatechin 3-gallate | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | US20240336588, Compound 3
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
c1c(cc(c(c1O)O)O)[C@@H]2[C@@H](Cc3c(cc(cc3O2)O)O)OC(=O)c4cc(c(c(c4)O)O)O
Structure:
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