Reaction Details Report a problem with these data
Target
Acid phosphatase
Ligand
BDBM59083
Substrate
n/a
Meas. Tech.
Inhibitor Screening Assay
Ki
5.9e+2± 2.3e+2 nM
Citation
 McRae, S; Pagliai, FA; Mohapatra, NP; Gener, A; Mahmou, AS; Gunn, JS; Lorca, GL; Gonzalez, CF Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J Biol Chem 285:5171-7 (2010) [PubMed]  Article 
Target
Name:
Acid phosphatase
Synonyms:
Acid phosphatase (acpA) | Acid phosphatase (acpB) | Acid phosphatase (acpC)
Type:
Enzyme
Mol. Mass.:
22350.38
Organism:
Francisella tularensis
Description:
Q5NIC0
Residue:
194
Sequence:
MTQQQVISYYESTAHENEVELILARAKKIIQAQQSLQGNAIVLDIDETALNHYYSLKLAGFPQGENHTIWNELLSRTDAYPIKATLDFYLYCLTSGLKVFFISARFAQYLESTKQALRNAGYVNFEDVFVFPENIEQYNSKDFKNFKAERRAYIESLGYKILISIGDQSSDLLGGYTLYTLQLPNYLYGENSRF
  
Inhibitor
Name:
BDBM59083
Synonyms:
MLS002154065 | SMR001233380 | THONZONIUM BROMIDE | Thonzonium | cid_11102
Type:
Small organic molecule
Emp. Form.:
C32H55N4O
Mol. Mass.:
511.8048
SMILES:
CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c1ncccn1
Structure:
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