Reaction Details Report a problem with these data
Target
Casein kinase II subunit alpha
Ligand
BDBM92607
Substrate
n/a
Meas. Tech.
Enzyme Assay
Temperature
303.1500±0.0000 K
Ki
1.039e+5± 9.1e+3 nM
Citation
 Chijiwa, T; Mishima, A; Hagiwara, M; Sano, M; Hayashi, K; Inoue, T; Naito, K; Toshioka, T; Hidaka, H Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 265:5267-72 (1990) [PubMed] 
Target
Name:
Casein kinase II subunit alpha
Synonyms:
CK2- alpha | Casein kinase II (CK2) | Casein kinase II alpha/beta | Casein kinase II subunit alpha (CK2 alpha) | Casein kinase II subunit alpha (CK2A1) | Casein kinase II subunit alpha (CK2a I174A) | Casein kinase II subunit alpha (CK2a V66A) | Casein kinase II subunit alpha (CK2a dm V66I174AA) | Casein kinase II subunit alpha (CK2a) | CK II | CK2 | CSK21_HUMAN | CSNK2A1 | CK2A1 | Casein kinase 2
Type:
Enzyme
Mol. Mass.:
45151.12
Organism:
Human
Description:
P68400
Residue:
391
Sequence:
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
  
Inhibitor
Name:
BDBM92607
Synonyms:
H-88
Type:
Small Molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
O=S(=O)(NCCNC\C=C\c1ccccc1)c1cccc2cnccc12
Structure:
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