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Target
cAMP-dependent protein kinase type I-alpha regulatory subunit
Ligand
BDBM50011236
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
7.4000±0.0000
Temperature
303.1500±0.0000 K
IC50
3.6e+3±n/a nM
Citation
 Chijiwa, T; Hagiwara, M; Hidaka, H A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. J Biol Chem 264:4924-7 (1989) [PubMed] 
Target
Name:
cAMP-dependent protein kinase type I-alpha regulatory subunit
Synonyms:
cAMP-dependent protein kinase | KAP0_BOVIN | PRKAR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42885.14
Organism:
Bovine
Description:
gi_115496662
Residue:
380
Sequence:
MASGTTASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAGSRADSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
  
Inhibitor
Name:
BDBM50011236
Synonyms:
Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide | Isoquinolinesulfonamide, H-9 | CHEMBL344314 | N-(2-aminoethyl)isoquinoline-5-sulfonamide
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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