Reaction Details Report a problem with these data
Target
Apoptosis regulator Bcl-2
Ligand
BDBM156394
Substrate
n/a
Meas. Tech.
Fluorescence Polarization
IC50
7±n/a nM
Citation
 Diebold, RB; Gero, T; Grover, P; Huang, S; Ioannidis, S; Ogoe, CA; Saeh, JC Chemical compounds US Patent  US9018381 Publication Date 4/28/2015 
Target
Name:
Apoptosis regulator Bcl-2
Synonyms:
Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | Bcl-2 Protein | BCL2_HUMAN | BCL2
Type:
Homodimer or heterodimer
Mol. Mass.:
26269.11
Organism:
Human
Description:
P10415
Residue:
239
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
  
Inhibitor
Name:
BDBM156394
Synonyms:
US9018381, 18 | US9018381, 17 | US9248140, 18
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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