Reaction Details Report a problem with these data
Target
Cyclin-dependent kinase 5
Ligand
BDBM164883
Substrate
n/a
Meas. Tech.
In Vitro Kinase Inhibition Assay
pH
7.5000±n/a
IC50
1077±n/a nM
Comments
extracted
Citation
 Zeitlmann, L; Niestroj, A; Heiser, U Inhibitors of protein kinases US Patent  US9067888 Publication Date 6/30/2015 
Target
Name:
Cyclin-dependent kinase 5
Synonyms:
Cyclin-dependent-like kinase 5 (CDK5) | Cyclin-dependent kinase 5 (CDK5/ p25) | Cyclin-dependent kinase 5 (CDK5/p35) | Cell division protein kinase 5 | Serine/threonine-protein kinase PSSALRE | Tau protein kinase II catalytic subunit | Cyclin-dependent-like kinase 5 | CDK5_HUMAN | CDK5 | CDKN5 | PSSALRE
Type:
Enzyme Subunit
Mol. Mass.:
33308.61
Organism:
Human
Description:
n/a
Residue:
292
Sequence:
MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
  
Inhibitor
Name:
BDBM164883
Synonyms:
US9067888, 33
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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