Reaction Details Report a problem with these data
Target
Adenosine receptor A3 [I248L]
Ligand
BDBM50310922
Substrate
n/a
Meas. Tech.
Fluorometric Imaging Plate Reader (FLIPR) Asssay
IC50
233.1±n/a nM
Citation
 Jordan, A; Bedford, S; Burkhard, K; Yule, I; Poullennec, K Thienopyrimidine compounds US Patent  US9120807 Publication Date 9/1/2015 
Target
Name:
Adenosine receptor A3 [I248L]
Synonyms:
Adenosine receptor A3 | AA3R_HUMAN | ADORA3 | Adenosine receptor A3 (A3)
Type:
Protein
Mol. Mass.:
36197.32
Organism:
Human
Description:
P0DMS8[I248L]
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSLINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50310922
Synonyms:
{6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2-d]pyrimidin-4-yl}-thiophen-2-yl-methanone | CHEMBL1080241 | US9120807, 9
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: