Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Apoptosis regulator Bcl-2 [1-204]
Ligand
BDBM156394
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
pH
7.5000±n/a
IC50
2±n/a nM
Comments
extracted
Citation
Diebold, RB; Gero, TW; Grover, P; Huang, S; Ioannidis, S; Ogoe, CA; Saeh, JC Chemical compounds US Patent US9248140 Publication Date 2/2/2016 More Info.:
Target
Name:
Apoptosis regulator Bcl-2 [1-204]
Synonyms:
BCL2_HUMAN | BCL2 | Apoptosis regulator Bcl-2
Type:
Protein
Mol. Mass.:
22461.03
Organism:
Human
Description:
C-terminal 6XHIS tagged Bcl-2 (aa 1-204)
Residue:
204
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP
Inhibitor
Name:
BDBM156394
Synonyms:
US9018381, 18 | US9018381, 17 | US9248140, 18
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
