Reaction Details Report a problem with these data
Target
Casein kinase II subunit beta
Ligand
BDBM219752
Substrate
BDBM220103
Meas. Tech.
Inhibition Assay
pH
7.0000±n/a
IC50
>1000±n/a nM
Comments
extracted
Citation
 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM Pyrazolopyrimidines and related heterocycles as CK2 inhibitors US Patent  US9303033 Publication Date 4/5/2016 
Target
Name:
Casein kinase II subunit beta
Synonyms:
Casein kinase II subunit beta (CK2β) | Casein kinase II subunit beta | Serine/threonine-protein kinase pim-2 | CSK2B_HUMAN | CSNK2B | CK2N | G5A | Casein kinase II subunit beta (CK2 beta)
Type:
Enzyme
Mol. Mass.:
24937.13
Organism:
Human
Description:
P67870
Residue:
215
Sequence:
MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
  
Inhibitor
Name:
BDBM219752
Synonyms:
US9303033, B48, Table 58A, Compound 25 | US9303033, H49, Table 59A, Compound 18 | US9303033, K36, Table 39A, Compound 59
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM220103
Synonyms:
US9303033, RSRSSYPAGT
Type:
Peptide Substrate
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: