Target
CHK1_Kinase
Ligand
BDBM225365
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
23.9±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed]
Target
Name:
CHK1_Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM225365
Synonyms:
Chk1_114
Type:
Small Organic Molecule
Emp. Form.:
C19H15N3O3
Mol. Mass.:
333.3407
SMILES:
CNC(=O)c1ccc2Cc3c(n[nH]c3-c3ccc(cc3)C(O)=O)-c2c1
Structure:
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