Target
CHK1_Kinase
Ligand
BDBM225366
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
1.6±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed]
Target
Name:
CHK1_Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM225366
Synonyms:
Chk1_115
Type:
Small Organic Molecule
Emp. Form.:
C24H20N2O3
Mol. Mass.:
384.4272
SMILES:
COc1cc2Cc3c(n[nH]c3-c3ccc(cc3)-c3ccc(O)cc3)-c2cc1OC
Structure:
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