Target
CHK1_Kinase
Ligand
BDBM91842
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
49.4±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed]
Target
Name:
CHK1_Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM91842
Synonyms:
Chk1_117
Type:
n/a
Emp. Form.:
C24H21N3O6
Mol. Mass.:
447.44
SMILES:
COC(=O)Cc1ccc2Nc3cc(c(C)cc3C(=O)Nc2c1)-c1ccc(c(OC)c1)[N+]([O-])=O
Structure:
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