Target
CHK1_Kinase
Ligand
BDBM91859
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
5.17±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed]
Target
Name:
CHK1_Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM91859
Synonyms:
Chk1_136
Type:
n/a
Emp. Form.:
C27H22N4O6
Mol. Mass.:
498.4868
SMILES:
COc1cc2NC(=O)c3ccc(cc3Nc2cc1OCc1ccncc1)-c1ccc(c(OC)c1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: