Target
GlcB
Ligand
BDBM225391
Substrate
n/a
Meas. Tech.
DNTB-Coupled_Enzyme_Assay
IC50
2700±n/a nM
Citation
 D3R, DD Sacchettini GlcB D3R 223:0 (2015) [PubMed]
Target
Name:
GlcB
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
80350.85
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
741
Sequence:
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGASKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
  
Inhibitor
Name:
BDBM225391
Synonyms:
Sacchettini_10
Type:
Small Organic Molecule
Emp. Form.:
C10H6ClFO4
Mol. Mass.:
244.604
SMILES:
OC(=O)C(=O)CC(=O)c1c(F)cccc1Cl
Structure:
Search PDB for entries with ligand similarity: